How does isolated systolic hypertension (ISH) differ from normal blood pressure readings in older adults?

Isolated systolic hypertension (ISH) in older adults is characterized by a systolic blood pressure (SBP) greater than 160 mm Hg and a diastolic blood pressure (DBP) of less than 90 mm Hg. In contrast, normal blood pressure readings do not exceed these values and typically have a lower SBP and a DBP that is not below 90 mm Hg.

In older adults, isolated systolic hypertension (ISH) is defined by a systolic blood pressure (SBP) that exceeds 160 mm Hg while the diastolic blood pressure (DBP) remains below 90 mm Hg. This condition is distinct from normal blood pressure readings, which do not reach such high systolic levels and maintain a diastolic pressure that is not below 90 mm Hg. ISH is significant because it poses a greater risk for cardiovascular events compared to diastolic hypertension, and aggressive treatment of ISH can significantly reduce the risk of stroke, myocardial infarction, and sudden cardiac death.