ExplanationIntermediate
What is the mechanism of action of venlafaxine as described in the chapter on antidepressants and mood stabilisers?
Venlafaxine acts as a noradrenaline-serotonin reuptake inhibitor (NSRI), blocking the reuptake of noradrenaline and serotonin, and to some extent, dopamine. Its inhibition of serotonin reuptake is greater than that of noradrenaline.
Key points
- Venlafaxine is classified as an NSRI.
- It blocks the reuptake of noradrenaline and serotonin.
- Dopamine reuptake is also affected, but to a lesser extent.
- The inhibition of serotonin reuptake is more pronounced than that of noradrenaline.
Source:Fundamentals of Pharmacology: An Applied Approach for Nursing and Health· Antidepressants and mood stabilisers· p. 368–376
Fundamentals of Pharmacology: An Applied Approach for Nursing and Health
Alan Galbraith ... [et Al.].
Second Edition · Routledge